Rendering shown. Your prescription arrives in Parke's unmarked packaging. Compounded medications are not FDA-approved.
GHK-Cu Cream RX
A copper peptide cream built on a molecule your own plasma carries. No needles and no miracle promises: a nightly topical protocol, a clinician who screens you first, and honesty about what the evidence does and does not show.
GHK-Cu Cream is a compounded medication, prepared for your prescription by Striker Pharmacy, a state-licensed US 503A compounding pharmacy. Compounded medications are not FDA-approved.
- 30 g of cream, a full 30-day supply, applied in about two minutes
- No needles anywhere in this protocol: a thin layer, nightly
- Free discreet delivery, every month
- Unlimited clinician messaging between refills
Your final plan and price are set with your clinician, and you can pause or cancel anytime.
A molecule you already make.
Here is what that means.
GHK-Cu is not an exotic invention. It is a small peptide found naturally in human plasma, bound to a copper ion, and compounded here as a nightly cream.
Three amino acids
GHK is a tripeptide: glycine, histidine, and lysine, one of the smaller peptides circulating in human plasma, first identified there in the 1970s.
Why it is blue
GHK binds copper tightly, and the resulting complex, GHK-Cu, carries a natural blue color. No dye is involved: the tint in the bottle is the chemistry itself.
Levels fall with age
Plasma GHK declines with age. That decline is documented; what applying the copper complex to skin does for adults is still being studied.
Topical, on purpose
A 30 g cream, applied in a thin layer at night after cleansing. It is the first Parke treatment with no needle anywhere in it.
Real chemistry, honestly framed.
Your clinician decides whether it fits you.
Two minutes, then done.
GHK-Cu is an evening habit, not a project. A thin layer after cleansing, and that is the whole protocol.
- A thin layer, nightly. On clean, dry skin, with guided instructions in your member portal. The bottle is measured to last the month.
- An honest word on the color. The copper complex makes the cream blue. It applies sheer and settles clear; give it a moment before a white pillowcase.
- A clinician on your side of it. Questions between refills are answered by your care team, usually the same business day.
Built for real life
A slow tissue, judged fairly.
Skin renews itself over weeks, not days. The protocol is built around that honesty. Yours may differ.
Learning the habit
A thin layer nightly on clean, dry skin, guided from your member portal. The first week is about the routine, not the results; most people find it takes about two minutes.
Giving skin time
The skin you can see today took weeks to reach the surface. Anything worth noticing tends to arrive gradually across the first months, which is why nobody should judge this in week two.
Only as long as it earns it
At the review you and your clinician decide together. If you cannot tell the difference after a fair trial, they will say so rather than keep shipping it.
Every refill is reviewed. Refills at Parke are approved by the clinician who knows your chart, never by an auto-renewal system. Adjustments, including pausing or stopping, are included in your plan.
Real chemistry,
early human evidence.
GHK is one of the smallest peptides in human plasma. The molecule is borrowed from your own biology, not invented for a label.
What is well established is the chemistry: GHK binds copper avidly, the complex occurs naturally in the body, and plasma levels decline with age. Copper peptides have been studied in skin-biology laboratories for five decades, which is longer than most of what sits on a cosmetics shelf.
What is not established is the payoff. Nearly all of that research is laboratory work or small cosmetic studies. None of it supports marketing GHK-Cu as an anti-aging, firming, or wound treatment, and Parke does not make those claims. What you receive is a compounded preparation, which is not FDA-approved or evaluated. Individual results vary, many people notice nothing, and nothing here is guaranteed.
The counter, reconsidered.
You don't have to choose alone. Your clinician weighs your skin, your history, and your goals, and will tell you plainly if GHK-Cu is not the right place to spend your money.
On GHK-Cu, in their words.
“The bottle lasted exactly the month, and the routine is two minutes after washing my face. Nobody promised me anything, which oddly is why I trusted it.”
“I asked my clinician point blank what the evidence shows and got a straight answer: mostly lab studies, early in adults. I decided a fair trial was worth it, on my terms.”
“The blue surprised me the first night; it settles clear. What kept me was the twelve-week check-in, an actual conversation about whether to continue.”
Individual results and experiences vary. Testimonials reflect the experiences of specific members and are not a guarantee of outcomes. Treatment is prescribed only when a licensed clinician determines it is appropriate.
Side effects, said plainly.
You deserve the whole picture before you start, not after.
Common, usually brief
- A brief sting or tingle when the cream goes on, the most commonly reported effect
- Temporary redness where it is applied
- Dryness, mild flaking, or itch, most often in the first weeks
- A faint tint on fabric if it has not settled before contact
Stop and message your clinician
- A rash that spreads beyond where you applied the cream
- Swelling, blistering, or weeping skin at the application area
- Hives, facial swelling, or trouble breathing: seek immediate care
- Irritation that persists or worsens instead of settling
How Parke handles this: your clinician screens your full history first, including any sensitivity to copper or topical products, active skin conditions at the application area, and pregnancy or breastfeeding, because prescribing even a topical responsibly means asking those questions. The cream is for external use only, kept away from the eyes, mouth, and broken skin, and your care team is reachable between refills, usually the same business day. Full details in the important safety information.
Asked, answered, plainly.
Can't find your question? Message us. A human on our care team replies, usually within a few hours.
GHK-Cu is a copper peptide: a chain of three amino acids (glycine, histidine, lysine) bound to a copper ion. The peptide occurs naturally in human plasma, and its levels decline with age. At Parke it is prescribed as a compounded 30 g topical cream by a licensed clinician, when appropriate, and prepared by Striker Pharmacy, a state-licensed US 503A compounding pharmacy.
That is the copper. When GHK binds a copper ion, the resulting complex has a natural blue color; no dye is added. It applies sheer and settles clear on the skin, though it can mark light fabric before it does.
Honestly: possibly nothing, and nothing quickly. Skin renews itself over weeks, and most of the research behind copper peptides is laboratory work or small cosmetic studies rather than rigorous adult trials. Some members describe gradual changes across the first months; others notice nothing and stop at the review. Your clinician will set that expectation before you spend anything, and the 12-week review is where you decide together whether it earned its place.
Mostly in the system around it. Cosmetic copper peptide products rarely disclose how much peptide they contain, and no clinician is involved in the purchase. Parke's cream is compounded to your prescription with a stated GHK-Cu content by a named, state-licensed US pharmacy, after a clinician has screened your history. The honest caveat applies on both sides of that comparison: the adult evidence for copper peptide skincare is early, wherever you buy it.
No. Compounded medications are not FDA-approved, and this cream is no exception. GHK-Cu for topical use appears on the FDA's list of substances nominated for use in 503A compounding and still under evaluation, which is why state-licensed pharmacies may compound it while that review is pending. That is a provisional status, not an approval, and Parke will say so plainly for as long as it is true.
Usually, but tell your clinician what you use. Your current products are part of the intake, and your clinician will tell you what to keep, what to move to mornings, and what to pause while you give the cream a fair trial, so that whatever you notice at the review can actually be attributed.
Eligibility is a clinical decision made from your full intake. GHK-Cu Cream is not prescribed with a known sensitivity to copper or any component of the preparation, is not applied to broken or actively inflamed skin, and is prescribed only cautiously during pregnancy or breastfeeding, among other factors your clinician reviews before anything is written. See the full eligibility page.
Everything: your medication, clinician reviews, unlimited care-team messaging, and free discreet shipping. No membership fees, no hidden charges, no cancellation fees, and you can pause or cancel anytime from your member portal.
Explore other concierge treatments.
Skincare with the claims stripped out starts with a conversation.
A private 2-minute assessment, read by a clinician who will decide with you: GHK-Cu, something else, or nothing at all.
No charge unless a clinician approves your plan · Pause or cancel anytime
Important safety information: compounded GHK-Cu topical cream
For external use only. Do not use if you are allergic or sensitive to GHK-Cu, copper, or any component of the preparation. Keep away from the eyes, mouth, and other mucous membranes, and do not apply to broken, infected, or actively inflamed skin. Tell your clinician if you are pregnant, breastfeeding, or planning pregnancy; have a condition affecting copper metabolism; have eczema, dermatitis, or another skin condition at the intended application area; or use other topical prescription products. The most commonly reported effects are brief stinging or tingling on application, temporary redness, and dryness, flaking, or itch at the application area. Rarely, allergic skin reactions (including spreading rash, swelling, or blistering) can occur; stop use and contact your clinician if they do, and seek immediate care for hives, swelling of the face or throat, or difficulty breathing.
GHK-Cu Cream is compounded for Parke prescriptions by Striker Pharmacy, a state-licensed US 503A compounding pharmacy, and, like all compounded medications, is not FDA-approved or evaluated by the FDA for safety, effectiveness, or quality. GHK-Cu is currently under FDA evaluation for use in 503A compounding; that status is provisional and is not an approval. Topical GHK-Cu has not been shown in rigorous clinical trials to firm skin, reduce wrinkles, heal wounds, slow or reverse skin aging, or treat any skin condition, and Parke does not prescribe or market it for those claims or as a substitute for sun protection, sleep, nutrition, or evaluation of any skin concern by a qualified professional. This page is informational, is not medical advice, and does not guarantee any outcome. If you are experiencing a medical emergency, call 911.