The Journal
An honest resource on metabolic health: articles from our clinicians, guest columns from trainers and dietitians, and plain answers to the questions our members actually ask. Written to be trusted, not to sell.
Browse by what you're wondering.
What the first 90 days of GLP-1 treatment actually involve
Cash pay, explained: what it is, and why it works in your favor
HSA and FSA, explained: paying for care with pre-tax dollars
Inside ParkeInside the 24-hour clinician review: what we look for
Why progress stalls at week 12, and what titration fixes
Titration, explained: why your dose starts low and climbs on a schedule
Retatrutide, explained: and why no one can legally prescribe it yet
GLP-1 and perimenopause: when the old rules stop working
GLP-1 and menopause: a new metabolism deserves new tools
GLP-1 and pregnancy: why the answer is stop, and how to plan
Food noise, explained by the hormone that quiets it
NutritionProtein first: the plate that protects muscle on a GLP-1
MovementStrength training on a smaller appetite: a coach's protocol
ScienceSleep, cortisol, and the scale: a triangle worth knowing
The quiet case for quarterly refills
ScienceHow to read a compounded prescription label
Semaglutide vs tirzepatide: the honest head to head comparison
How GLP-1s actually work: the mechanism in plain language
The GLP-1 results timeline: what happens when, honestly
GLP-1 side effects: the honest guide to what happens and what helps
GLP-1s and hair loss: why shedding happens, and how it grows back
The loose skin question: what weight loss changes, and what helps
What to eat on a GLP-1: the guide with no forbidden foods
GLP-1s and alcohol: what actually changes when you drink
What happens when you stop a GLP-1, and what stays yours
Your first injection: a calm, step by step walkthrough for night one
Microdosing GLP-1s: a reasonable impulse, and a risky way to act on it
Keeping the weight off: what maintenance actually asks of you
Microdosing semaglutide: what a lower dose can and cannot do
Microdosing tirzepatide: a sliver of the stronger molecule, examined
Does NAD+ actually work? The evidence, graded honestly
Do B12 shots work? Myths, facts, and the promise you should never believe
GLP-1 nausea: why it happens, when it fades, and what actually helps
GLP-1 constipation: the quiet side effect, and the plan that fixes it
Tired on a GLP-1? Why energy dips early, and what restores it
Heartburn and reflux on a GLP-1: what is happening, and what calms it
Injection site reactions: redness, bruising, lumps, and what they mean
Dizzy after a GLP-1 dose: the blood pressure, hydration, and sugar check
Pancreatitis and GLP-1s: the actual risk and the warning signs
Gallstones and rapid weight loss: why the gallbladder complains
The thyroid warning on every GLP-1 label, explained without alarm
GLP-1s and mood: what the evidence says about anxiety and depression
Missed a dose? The rules for semaglutide and tirzepatide, day by day
Changing your injection day: the 48-hour rule and how to plan around travel
Traveling with a GLP-1: storage, airport security, and the cold chain at 35,000 feet
How to store your vials and pens: fridge, room temperature, and the 28-day clock
When a GLP-1 does not seem to work: non-responders, wrong dose, or wrong expectations
The month-six plateau: why the scale stops, and the four questions your clinician asks
Switching from semaglutide to tirzepatide: how clinicians do it, and what to expect
The dose ladder: every semaglutide and tirzepatide step, and why each rung exists
GLP-1 drug interactions: the medications that need a second look before you start
GLP-1s and birth control: the tirzepatide pill warning, and what to do about it
The archive stays free, whether or not you're a member.
People who do this for a living.
Every article is written or reviewed by a licensed clinician. Guest columns come from working professionals, named and credentialed, never content farms.
Start with the fundamentals.
Four pages that explain the whole system: who qualifies, how it works, and what each treatment does.
Eligibility & how it works
The full process, from a 2-minute intake to your next refill.
02Tirzepatide, explained
The dual-action GLP-1 + GIP option and who it's for.
03MIC + B12, explained
Nutrient support, said plainly: what it is and what it isn't.
04The Method
Our most considered level of care, for those who want depth.
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About this journal
Articles in the Parke Journal are for general information and education. They are not medical advice, do not create a clinician-patient relationship, and are not a substitute for care from a licensed clinician who knows your history. Guest columns reflect the views of their credited authors. Compounded medications discussed in these pages are not FDA-approved and are not evaluated by the FDA for safety, effectiveness, or quality; review the important safety information on each treatment page. If you are experiencing a medical emergency, call 911.
