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The Journal

An honest resource on metabolic health: articles from our clinicians, guest columns from trainers and dietitians, and plain answers to the questions our members actually ask. Written to be trusted, not to sell.

Written by clinicians and coaches Medically reviewed No hype, no miracle claims
The library

Browse by what you're wondering.

GLP-1

What the first 90 days of GLP-1 treatment actually involve

14 min read

Inside Parke

Cash pay, explained: what it is, and why it works in your favor

9 min read

Inside Parke

HSA and FSA, explained: paying for care with pre-tax dollars

8 min read

A clinician in a white coat reviewing member messages on a phoneInside Parke

Inside the 24-hour clinician review: what we look for

8 min read

GLP-1

Why progress stalls at week 12, and what titration fixes

9 min read

Science

Titration, explained: why your dose starts low and climbs on a schedule

7 min read

Science

Retatrutide, explained: and why no one can legally prescribe it yet

8 min read

GLP-1

GLP-1 and perimenopause: when the old rules stop working

8 min read

GLP-1

GLP-1 and menopause: a new metabolism deserves new tools

8 min read

GLP-1

GLP-1 and pregnancy: why the answer is stop, and how to plan

9 min read

Science

Food noise, explained by the hormone that quiets it

7 min read

A woman cooking dinner at home in a warm kitchenNutrition

Protein first: the plate that protects muscle on a GLP-1

8 min read

A member at home in the evening with a glass of waterMovement

Strength training on a smaller appetite: a coach's protocol

10 min read

A bright, calm living room at homeScience

Sleep, cortisol, and the scale: a triangle worth knowing

8 min read

Inside Parke

The quiet case for quarterly refills

5 min read

Parke compounded semaglutide vial, label facing forwardScience

How to read a compounded prescription label

6 min read

GLP-1

Semaglutide vs tirzepatide: the honest head to head comparison

14 min read

Science

How GLP-1s actually work: the mechanism in plain language

13 min read

GLP-1

The GLP-1 results timeline: what happens when, honestly

13 min read

GLP-1

GLP-1 side effects: the honest guide to what happens and what helps

15 min read

GLP-1

GLP-1s and hair loss: why shedding happens, and how it grows back

12 min read

GLP-1

The loose skin question: what weight loss changes, and what helps

13 min read

Nutrition

What to eat on a GLP-1: the guide with no forbidden foods

15 min read

Nutrition

GLP-1s and alcohol: what actually changes when you drink

13 min read

GLP-1

What happens when you stop a GLP-1, and what stays yours

13 min read

GLP-1

Your first injection: a calm, step by step walkthrough for night one

14 min read

Science

Microdosing GLP-1s: a reasonable impulse, and a risky way to act on it

14 min read

GLP-1

Keeping the weight off: what maintenance actually asks of you

13 min read

Science

Microdosing semaglutide: what a lower dose can and cannot do

13 min read

Science

Microdosing tirzepatide: a sliver of the stronger molecule, examined

14 min read

Science

Does NAD+ actually work? The evidence, graded honestly

13 min read

Science

Do B12 shots work? Myths, facts, and the promise you should never believe

12 min read

GLP-1

GLP-1 nausea: why it happens, when it fades, and what actually helps

11 min read

GLP-1

GLP-1 constipation: the quiet side effect, and the plan that fixes it

9 min read

GLP-1

Tired on a GLP-1? Why energy dips early, and what restores it

9 min read

GLP-1

Heartburn and reflux on a GLP-1: what is happening, and what calms it

8 min read

GLP-1

Injection site reactions: redness, bruising, lumps, and what they mean

7 min read

GLP-1

Dizzy after a GLP-1 dose: the blood pressure, hydration, and sugar check

8 min read

GLP-1

Pancreatitis and GLP-1s: the actual risk and the warning signs

10 min read

GLP-1

Gallstones and rapid weight loss: why the gallbladder complains

9 min read

Science

The thyroid warning on every GLP-1 label, explained without alarm

10 min read

Science

GLP-1s and mood: what the evidence says about anxiety and depression

11 min read

GLP-1

Missed a dose? The rules for semaglutide and tirzepatide, day by day

7 min read

GLP-1

Changing your injection day: the 48-hour rule and how to plan around travel

6 min read

Inside Parke

Traveling with a GLP-1: storage, airport security, and the cold chain at 35,000 feet

8 min read

Inside Parke

How to store your vials and pens: fridge, room temperature, and the 28-day clock

6 min read

GLP-1

When a GLP-1 does not seem to work: non-responders, wrong dose, or wrong expectations

10 min read

GLP-1

The month-six plateau: why the scale stops, and the four questions your clinician asks

10 min read

GLP-1

Switching from semaglutide to tirzepatide: how clinicians do it, and what to expect

9 min read

Science

The dose ladder: every semaglutide and tirzepatide step, and why each rung exists

10 min read

Science

GLP-1 drug interactions: the medications that need a second look before you start

11 min read

GLP-1

GLP-1s and birth control: the tirzepatide pill warning, and what to do about it

8 min read

The archive stays free, whether or not you're a member.

Who writes this

People who do this for a living.

Every article is written or reviewed by a licensed clinician. Guest columns come from working professionals, named and credentialed, never content farms.

Dr. Alana Reyes, MD Medical Director · Internal Medicine
Dr. Marcus Okafor, MD Lead Clinician · Obesity Medicine
Dr. Priya Shah, MD Endocrinology
Lena Ortiz, RD Registered Dietitian · Guest columnist
Danny Rivera, CSCS Strength Coach · Guest columnist

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About this journal

Articles in the Parke Journal are for general information and education. They are not medical advice, do not create a clinician-patient relationship, and are not a substitute for care from a licensed clinician who knows your history. Guest columns reflect the views of their credited authors. Compounded medications discussed in these pages are not FDA-approved and are not evaluated by the FDA for safety, effectiveness, or quality; review the important safety information on each treatment page. If you are experiencing a medical emergency, call 911.